Copeptin and Stress

Vasopressin (AVP) and copeptin are released in equimolar amounts from the same precursor. Due to its molecular stability countless advantages as compared with AVP, perfectly mirrors AVP presence has progressively emerged a reliable marker of vasopressinergic activation response osmotic hemodynamic stimuli clinical practice. Moreover, evidence highlighting prognostic potential several acute diseases, where system is primarily linked stress, well psychologically stressful conditions, emerged. Furthermore, organic stressors induce rise levels which, although non-specific, unrelated plasma osmolality but proportional their magnitude: suggesting disease severity, proved be biomarker such sepsis, early post-surgical period, cardiovascular, cerebrovascular or pulmonary even critical settings. Evidence on this topic will briefly discussed article.